Patents and Patents pending:
Ari, C., Arnold P., D`Agostino, D.P. Technology Title: “Exogenous Ketone Supplements for Reducing Anxiety-Related Behavior”
Ari, C., Arnold P., D`Agostino, D.P. Technology Title: “Elevated Blood Ketone Levels by Ketogenic Diet or Exogenous Ketone Supplements Induced Increased Latency of Anesthetic Induction”
Ari, C., Arnold P., D`Agostino, D.P. Technology Title: “Exogenous Ketone Supplementation Improved Motor Function in Sprague-Dawley Rats.”
Ari, C., Arnold P., D`Agostino, D.P. Technology Title: “Lowering of Blood Glucose in Exercising and Non-Exercising Rats Following Administration of Exogenous Ketones and Ketone Formulas.”
Ari, C., Arnold P., D`Agostino, D.P. Technology Title: “Neuroregeneration improved by ketone.”
Ari, C., D`Agostino, D.P. Dean, J.B. Technology Title: “Delaying latency to seizure by combinations of ketone supplements.”
Kovacs, Zs., Ari, C., D`Agostino, D.P., Brunner, B., Rauch, E. Technology Title: "Ketone supplements-evoked effect on absence epilepsy by co-administration of uridine."
Book
1. Ari, C. (2009). On the brain of cartilaginous fishes: Cerebralization, astroglial architecture and blood-brain barrier composition, Lambert Academic Publishing.
Book chapter
1. Ari, C., Pilla, R., D’Agostino, D.P. (2014) Nutritional/Metabolic therapies in animal models of ALS, Alzheimer’s disease, and seizures, in: Bioactive Nutriceuticals and Food Supplements in Neurological and Brain Disease, http://dx.doi.org/10.1016/B978-0-12-411462-3.00047-3
2. Poff AM, Annis HA, Whelan HT, Ari C, D’Agostino DP. (2017) Ketogenic Diet and Ketogenic Supplementation for Central Nervous System Oxygen Toxicity, Hyperbaric Medicine Practice, ISBN: 978-1-947239-005
3. Zsolt Kovacs, Dominic P. D’Agostino, and Csilla Ari (2022) Neuroprotective and Behavioral Benefits of Exogenous Ketone Supplementation-Evoked Ketosis, Ketogenic Diet and Metabolic Therapies: Expanded Roles in Health and Disease (2 ed.) Edited by: Susan A. Masino Oxford University Press DOI: 10.1093/med/9780197501207.001.0001
Articles
4. Kálmán, M., Ari, C. (2002). Distribution of GFAP immunoreactive structures in the rhombencephalon of sterlet (Acipenser ruthenus) and its evolutionary implication; Journal of Experimental Zoology, 2002, 293: 395-406.
5. Gál, J., Vincze, Z., Jakab, C., Ari, C., Lefler, K.K. (2005). Multiplex shafted fibroma on the upper jaw of a sand-tiger shark (Carcharias (Odontaspis)taurus); Hungarian Veterinary Journal, 127:242-245.
6. Ari, C., Kálmán, M. (2008). Evolutionary changes of astroglia in Elasmobranchii comparing to Amniotes: a study based on three immunohistochemical markers (GFAP, S-100, and glutamine synthetase), Brain, Behavior and Evolution, 71:305-324.
7. Ari, C., Kálmán, M. (2008). Glial architecture of the ghost shark (Callorinchus millii, Holocephalii, Chondrichthyes) as revealed by different immunohistochemical markers, Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Vol 310B, 6: 504 – 519.
8. Ari, C., Correia, J.P. (2008). Role of sensory cues on the food searching behaviour of a captive Manta birostris (Myliobatiformes, Mobulidae), Zoo Biology Vol 27, 4: 294 – 304.
9. Ari, C. (2011). Encephalization and brain organization of mobulid rays (Myliobatiformes, Elasmobranchii) with ecological perspectives, The Open Anatomy Journal 3:1-13.
10. Kitchen-Wheeler, A-M., Ari, C., Edwards, A.J. (2012) Population estimates of Alfred mantas (Manta alfredi) in central Maldives atolls: North Male, Ari and Baa, Environmental Biology of Fishes, 93:4, 557-575.
11. Kalman, M., Somiya, H., Lazarevic, L., Ari, C., Majorossy, K. (2013) Absence of post-lesion glial reactivity in elasmobranchs and turtles and its bearing on the evolution of astroglia, Journal of Experimental Zoology, doi: 10.1002/jez.b.22505.
12. D'Agostino, D., Pilla, R., Held, H., Landon, C.S., Ari, C., Puchowicz, M., Brunengraber, H., Arnold, P., Dean, J. (2013) Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats, American Journal of Physiology ;304(10): R829-36.
13. Poff, A., Ari, C., Seyfried, T., D`Agostino P.D. (2013) The Ketogenic Diet and Hyperbaric Oxygen Therapy Act Synergistically to Prolong Survival in Mice with Systemic Metastatic Cancer, PlosOne 8(6): e65522. doi:10.1371/journal.pone.0065522.
14. Ari, C., Borysov, S., Wu, J., Padmanabhan, J., Potter, H. (2014) Alzheimer amyloid beta
inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function. Neurobiol Aging. 35 (8): 1839-49. pii: S0197-4580(14)00180-8doi:10.1016/j.neurobiolaging.2014.02.006.
15. Poff, A.M., Ari, C., Arnold, P., Seyfried T.N., D’Agostino D.P. (2014) Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer, Int J Cancer. Feb 26. doi: 10.1002/ijc.28809
16. Ari, C. (2014) Rapid coloration changes of manta rays (Mobulidae), Biological Journal of Linnean Society, 113: 180–193. doi: 10.1111/bij.12321
17. Ari, C., Poff, A.M., Held, H., Fiorelli, T., Goldhagen, C., D`Agostino, D.P. (2014) Increased TCA cycle intermediates in response to diet with Deanna protocol in ALS mouse model The FASEB Journal vol. 28 no. 1 Supplement 578.3
18. Ari, C., Poff, A.M., Held, H.E., Landon, C.S., Goldhagen, C.R., Mavromates, N., D’Agostino, D.P. (2014) Metabolic therapy with Deanna Protocol Supplementation Delays Disease Progression and Extends Survival in Amyotrophic Lateral Sclerosis (ALS) Mouse Model, PLoS ONE 9(7): e103526. doi:10.1371/journal.pone.0103526
19. Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, Sherwood JW, Arnold P, D’Agostino DP. Effect of Sustaining Dietary Ketosis on the Hippocampal and Serum Metabolome of Sprague-Dawley Rats. March 2015, Boston, MA. The FASEB Journal, vol. 29 no. 1 Supplement 745.4.
20. Ari, C. (2015) Long-term body pigmentation changes on a manta ray (Mobulidae), Biological Journal of the Linnean Society, 114: 406–414. doi: 10.1111/bij.12416
21. Ari, C., Decker, S., Ford, J., D`Agostino, D.P. (2015) What can we learn from deep-diving elasmobranchs to help humans adapt to extreme underwater environments? The FASEB Journal, Vol. 29: 1, Supplement 678.18.
22. Ari, C., Poff, A., Landon, C., Goldhagen, C.R., Mavromates, N., Kesl, S., Ward N.P., Fiorelli T.N., Van Putten A.J., Sherwood J.W., Arnold P., D’Agostino, D.P. (2015) Metabolic therapies improve mitochondrial morphology and function, The FASEB Journal, Vol.. 29:1 Supplement 1036.10.
23. Kesl, S.L, Poff, A.M., Ward, N.P., Fiorelli, T.N., Ari, C., Van Putten, A.J., Sherwood, J.W., Arnold, P., D’Agostino, D.P. (2016) Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague–Dawley rats, Nutrition and Metabolism, 13:9. DOI: 10.1186/s12986-016-0069-y
24. Sajan, M., Hansen, B., Ivey, III R., Sajan, J., Ari, C., Song, S., Braun, U., Leitges, M., Farese-Higgs, M., Farese, R. (2016) Brain Insulin Signaling is Increased in Insulin-Resistant States and Decreases in FoxOs and PGC-1α and Increases in Aβ1-40.42 and Phospho-Tau May Abet Alzheimer Development. Diabetes. pii: db151428. PubMed PMID:26895791.
25. Ari, C., D’Agostino D.P. (2016) Contingency checking and self-directed behaviors in giant manta rays: Do elasmobranchs have self-awareness? Journal of Ethology, May 2016, Volume 34, Issue 2, pp 167-174.
26. Ari C, Laros K, Balcombe J, D`Agostino DP. (2016) Understanding the behavior of manta rays: response to a critique, Journal of Ethology, Volume 35, Issue 1, pp 149–152.
27. Ari C, Kovacs Z, Juhasz G, Murdun C, Goldhagen CR, Koutnik A, Poff AM, Kesl SL, D’Agostino DP. (2017) Exogenous ketone supplements reduce anxiety-related behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk rats. Front. Mol. Neurosci. 9:137. doi: 10.3389/fnmol.2016.00137
28. Ari C. Canfield CE; Copes N, Poff AM, Fiorelli TN, Landon CS, Goldhagen CR, Mavromates N, D’Agostino DP. (2017) The Deanna protocol supplement complex supports mitochondrial energy metabolism and prolongs lifespan in preclinical models of amyotrophic lateral sclerosis (ALS), Metabolomics, 13:55.
29. Kovacs Z, D'Agostino PD, Dobolyi A, Ari C. (2017) Adenosine A1 receptor antagonism abolished the anti-seizure effects of exogenous ketone supplementation in Wistar Albino Glaxo Rijswijk rats, Frontiers in Molecular Neuroscience, doi: 10.3389/fnmol.2017.00235
30. Kovács Z, D’Agostino DP, Ari C. (2018) Anxiolytic effect of exogenous ketone supplementation is abolished by adenosine A1 receptor inhibition in Wistar Albino Glaxo/Rijswijk rats, Frontiers in Behavioral Neuroscience, 12:29. doi: 10.3389/fnbeh.2018.00029
31. Ari C, Kovács Z, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Diamond D, D’Agostino DP. (2018) Nutritional ketosis delays the onset of isoflurane induced anesthesia, BMC Anesthesia,18:85.
32. Csilla Ari, Andrew P. Koutnik, Janine DeBlasi, Carol Landon, Christopher Q. Rogers, John Vallas, Sahil Bharwani, Michelle Puchowicz, Ilya Bederman, David Diamond, Mark S. Kindy, Jay B. Dean, Dominic P. D`Agostino (2019) Delaying Latency to Hyperbaric Oxygen-Induced CNS Oxygen Toxicity Seizures by Combinations of Exogenous Ketone Supplements, Physiological Reports, Vol 7:1, doi.org/10.14814/phy2.13961
33. Ari, C., D’Agostino, D. P., Diamond, D. M., Kindy, M., Park, C., Kovács, Z. (2019) Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements. J. Vis. Exp. (143), e58396, doi:10.3791/58396.
34. Kovács, Z., D'Agostino, D.P., Diamond, D.M., Ari, C. (2019) Exogenous Ketone Supplementation Decreased the Lipopolysaccharide-Induced Increase in Absence Epileptic Activity in Wistar Albino Glaxo Rijswijk Rats. Front. Mol. Neurosci. 12:45. doi: 10.3389/fnmol.2019.00045
35. Kovács Z, D’Agostino DP, Diamond D, Kindy MS, Rogers C and Ari C (2019) Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature. Front. Psychiatry 10:363. doi: 10.3389/fpsyt.2019.00363
36. Ari C, Cem Murdun, Andrew P. Koutnik, Craig R. Goldhagen, Christopher Rogers, Collin Park, Sahil Bharwani, David M. Diamond, Mark S. Kindy, Dominic P. D’Agostino, Zsolt Kovács (2019) Exogenous ketones lower blood glucose levels in rested and exercised rodent models. Nutrients, 11, 2330. doi: 10.3390/nu11102330
37. Kovács, Z., Brunner, B., D’Agostino, D.P., Ari, C. (2020) Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats. BMC Anesthesiol 20, 30 https://doi.org/10.1186/s12871-020-0943-z
38. Ari, C., Bharwani, S., Rehsi, A., Moss, S., Schmer-Galunder, S., Fiore, S., D`Agostino, D.P., Changes in Sensory Functions in Response to Living in an Extreme Underwater Saturation Environment. The FASEB Journal, 2020. 34(S1): p. 1-1.
39. Ari, C., D`Agostino, D.P., Bharwani, S., Rehsi, A., Moss, S., Schmer-Galunder, S., Fiore, S., Changes in Individual and Team Cognition in High Stress Extreme Underwater Saturation Environment Under Intense Workload. The FASEB Journal, 2020. 34(S1): p. 1-1.
40. Ari, C., D`Agostino, D.P., Bharwani, S., Rehsi, A., Moss, S., Schmer-Galunder, S., Fiore, S., Changes in Motor Function in Response to Living in an Extreme Underwater Saturation Environment under High Stress and Increased Workload. The FASEB Journal, 2020. 34(S1): p. 1-1.
41. Ari, C.; Murdun, C.; Goldhagen, C.; Koutnik, A.P.; Bharwani, S.R.; Diamond, D.M.; Kindy, M.; D’Agostino, D.P.; Kovacs, Z. Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models. Nutrients 2020, 12, 2459. https://doi.org/10.3390/nu12082459
42. Kovács Z, Brunner B, D’Agostino DP and Ari C (2021) Age- and Sex-Dependent Modulation of Exogenous Ketone Supplement-Evoked Effects on Blood Glucose and Ketone Body Levels in Wistar Albino Glaxo Rijswijk Rats. Front. Neurosci. 14:618422. doi: 10.3389/fnins.2020.618422
43. Koutnik AP, Favre ME, Noboa K, Sanchez-Gonzalez MA, Moss SE, Goubran B, Ari C, Poff AM, Rogers CQ, DeBlasi JM, Samy B, Moussa M, Serrador JM and D’Agostino DP (2021) Human Adaptations to Multiday Saturation on NASA NEEMO. Front. Physiol. 11:610000. doi: 10.3389/fphys.2020.610000
44. Brunner, B.; Rauch, E.; Ari, C.; D’Agostino, D.P.; Kovács, Z. Enhancement of Ketone Supplements-Evoked Effect on Absence Epileptic Activity by Co-Administration of Uridine in Wistar Albino Glaxo Rijswijk Rats. Nutrients 2021, 13, 234. https://doi.org/10.3390/nu13010234
45. Gambardella I, Ascione R, D’Agostino DP, et al. Neuroprotection of ketosis in acute injury of the mammalian central nervous system: A meta-analysis. J Neurochem. 2021;158:105– 118. https://doi.org/10.1111/jnc.15341
46. Ari, C., Park, C., Vallas, J., Sanford, R., Bharwani, S., Cha, B., Kindy, M. and D'Agostino, D. (2021), Changes in Density and Localization of GLUT1 and MCT1 Transporters of Cancer Cells Induced by Ketones. The FASEB Journal, 35:. https://doi.org/10.1096/fasebj.2021.35.S1.03574
47. Kovács, Z.; Brunner, B.; Ari, C. Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases. Nutrients 2021, 13, 2197. https://doi.org/10.3390/nu13072197
48. Medeiros AM, Ari C, Monteiro-Filho ELA (2021) Environmental factors involved in breaching behavior of manta rays in estuarine waters. Mar Ecol Prog Ser 674:203-219. https://doi.org/10.3354/meps13815
49. Brunner, B.; Ari, C.; D’Agostino, D.P.; Kovács, Z. Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats. Nutrients 2021, 13, 4082. https://doi.org/10.3390/nu13114082
50. Walson, F., Thomas, N., Poff, A.M., Alnajar, R., Johnson, A., Ari, C., Visovski, C., Matthew, K., Hull, A. and D'Agostino, D.P. (2022), Improving Emotional Well-Being and Cardio-Metabolic Health with Continuous Glucose Monitoring. The FASEB Journal, 36:. https://doi.org/10.1096/fasebj.2022.36.S1.R4527
51. Medeiros, A.M., Bersano, J.G.F., Ari, C. et al. Endangered mobulids within sustainable use protected areas of southeastern Brazil: occurrence, fisheries impact, and a new prey item. Environ Biol Fish 105, 775–786 (2022). https://doi.org/10.1007/s10641-022-01282-0
Presented posters
1. Ari, C., Kálmán, M. (2001) Search for astroglia in the GFAP-free areas of the brains of cartilagineous and bony fishes applying immunohistochemical staining of glutamine syntethase and S-100 protein; Conference of the Hungarian Neurobiological Society, Szeged, Hungary
2. Kálmán, M., Ari, C. (2001) Comparative study of astroglial markers, GFAP, glutamine syntethase and S-100 in skate brain; 96. Versammlung in Münster, Germany
3. Ari, C., Kálmán, M. (2003) Supposed sexual dimorphism on the cerebellum of the ray Mobula japanica (order Myliobatiformes); Joint Meeting of Ichthyologists and Herpetologists and the American Elasmobranch Society, Manaus, Brazil
4. Kálmán, M., Ari, C., Gould, R.M. (2003) Similar tendencies in the evolution of astroglia in elasmobranchs and amniotes. Joint Meeting of Ichthyologists and Herpetologists and the American Elasmobranch Society, Manaus, Brazil
5. Ari, C., Kálmán, M. (2003) Morphometrical studies on the cerebellum of a ray species (Mobula japanica) of the order Myliobatiformes- sexual dimorphism?; Conference of the Hungarian Neurobiological Society, Balatonfüred, Hungary
6. Ari, C., Stuber, I. (2004) Three-dimensional movements of captive Mobulids (Manta birostris and Mobula mobular); European Elasmobranch Society meeting, London, England
7. Ari, C., Kálmán, M., Correia, J.P., Stuber, I. (2004) Analysis of movements by computerised tridimensional video reconstruction; Neuroscience Meeting, San Diego, USA
8. Ari, C., Correia, J.P. (2005) A study on the sensory and learning capabilities of a captive Manta birostris (Mobulidae); Joint Meeting of Ichthyologists and Herpetologists and the American Elasmobranch Society Meeting, Tampa, USA
9. Kálmán, M., Ari, C. (2007) Evolutionary correlations of brain structure and glial architecture in Chondrichthyes: forebrain and hindbrain. 5th European Conference of Comparative Neurobiology, Paris, France
10. Ari, C. (2008) The brain of Mobula japanica (Myliobatiformes, Elasmobranchii) in gross morphological and ecological perspectives, Joint Meeting of Ichthyologists and Herpetologists and the American Elasmobranch Society Meeting, Montreal, Canada
11. Ari, C., Borysov, S.I., Wu, J., Padmanabhan, J., Potter, H. (2011) Aβ inhibits specific kinesin motors involved in both mitosis and neuronal function; potential implications for neurogenesis and neuroplasticity in Alzheimer’s Disease and Down Syndrome, International Conference on Alzheimer's Disease, Paris, France
12. Ari, C., Borysov, S., Wu, J., Padmanabhan, J., Potter, H. (2011) Impairment of neurotransmitter and neurotrophin receptor localization and function associated with Alzheimer`s disease is caused by Aβ inhibition of mitotic/neuronal kinesin Eg5, 41th Society for Neuroscience Conference, Washington, USA
13. D'Agostino DP, Pilla R, Dean JB, Ari C, Bennett A, Kesl S, Diamond D. (2011) Ketogenesis as a Therapeutic Strategy for CNS Oxygen Toxicity and Other Neurological Disorders. Society for Neuroscience Journal; San Diego, CA
14. Bennett, A., Ari, C., Kesl, S., Luke, J., Diamond, D., Dean, J., D'Agostino, D. (2012) Effect of ketone treatment and glycolysis inhibition in brain cancer cells (U87MG) and rat primary cultured neurons exposed to hyperbaric oxygen and amyloid beta, Experimental Biology, San Diego, USA
15. D'Agostino, D., Pilla, R., Held, H., Landon, C., Ari, C., Arnold, P., Dean, J.B. (2012) Development, testing and therapeutic applications of ketone esters (KE) for CNS oxygen toxicity (CNS-OT); i.e., hyperbaric oxygen (HBO2)-induced seizures, Experimental Biology, San Diego, USA
16. Bennett AM, Ari C, Kesl S, Luke J, Diamond D, Dean JB, D’Agostino DP. (2012) Effect of ketone treatment and glycolysis inhibition in brain cancer cells (U87MG cultures) and primary cultured neurons exposed to hyperbaric oxygen and amyloid beta (Ab). Federation of American Societies for Experimental Biology Journal, San Diego, CA, USA
17. D’Agostino DP, Bennett A, Pilla R, Held, HE, Ari C, and Dean J.B. (2012) Neuroprotective effects of ketone esters for CNS oxygen toxicity and other neurological disorders. 8th Federation of European Neuroscience Societies Forum; Barcelona, Spain. FENS Abstr. 2902, Present. Code 104.13
18. D'Agostino DP, Pilla R, Dean JB, Ari C, Bennett A, Kesl S, Diamond D. (2011) Ketogenesis as a Therapeutic Strategy for CNS Oxygen Toxicity and Other Neurological Disorders. Society for Neuroscience Journal; San Diego, CA,USA
19. Ari, C. (2012) Visual Abilities and Social Interaction of Manta Rays with the Largest Brain of Fishes and the Possible Underlying Neurological Structures, international Behavioral Neuroscience Society, Kona, HI, USA
20. Poff AM, Ari C, Goldhagen C, Seyfried T, D’Agostino D. (2013) Supplemental ketone metabolic therapy slows tumor growth and increases survival time in mice with metastatic cancer. Federation of American Societies for Experimental Biology Journal; Boston, MA.
21. Poff AM, Ari C, Goldhagen C, Seyfried TN, D’Agostino D. (2013) The ketogenic diet and hyperbaric oxygen therapy work synergistically to slow tumor growth and increase survival time in mice with systemic metastatic cancer. Federation of American Societies for Experimental Biology Journal; Boston, MA.
22. Ari, C., Poff, A., Held, H., Landon, C., Goldhagen, C.R., Mavromates, N., D’Agostino, D.P. (2013) Effect of alternative metabolic fuels as a potential ALS therapy in mice and humans, Ancestral Health Symphosium, Atlanta, USA
23. Ari, C., Poff, A., Held, H., Landon, C., Goldhagen, C.R., Mavromates, N., D’Agostino, D.P. (2013) Metabolic therapy with arginine alpha-ketoglutarate extends survival in Amyotrophic Lateral Sclerosis (ALS) mouse model , Society for Neuroscience, San Diego, USA
24. Poff, A., Ari, C., Goldhagen, C.R., Seyfried, T.N., D’Agostino, D.P. (2013) Effects of the ketogenic diet, supplemental ketone administration, and hyperbaric oxygen therapy on the VM-M3 mouse model of metastatic cancer, Society for Neuroscience, San Diego, USA
25. Bennett AM, Ari C, Kesl S, Luke J, Diamond D, Dean JB, D’Agostino DP. (2012) Effect of ketone treatment and glycolysis inhibition in brain cancer cells (U87MG cultures) and primary cultured neurons exposed to hyperbaric oxygen and amyloid beta (Ab). Federation of American Societies for Experimental Biology Journal; San Diego, CA, USA
26. Ari, C., D’Agostino, D.P. (2014) Neuroprotection of Ab treated hippocampal neurons during hyperbaric treatment with ketone supplementation, Alzheimer`s Disease International Conference, San Juan, Puerto Rico
27. Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, D’Agostino DP. (2014) Methods of sustaining dietary ketosis in Sprague-Dawley rats. Federation of American Societies for Experimental Biology Journal, San Diego, CA
28. Ari, C. , D`Agostino, D.P. (2014) Contingency Checking and Self-Directed Behaviors in Giant Manta Rays: Do Fish Have Self-Awareness?, American Elasmobranch Society Meeting, Chattanooga, USA
29. Ari, C., Poff, A., Held, H., Landon, C., Goldhagen, C.R., Mavromates, N., Kesl, S., Ward N.P., Fiorelli T.N., Van Putten A.J., Sherwood J.W., Arnold P., D’Agostino, D.P. (2014) Improving mitochondrial morphology and function by metabolic therapies, Ketogenic diet therapies, Liverpool, UK
30. Ari, C., Decker, S., Ford, J., D`Agostino, D.P. (2015) What can we learn from deep-diving elasmobranchs to help humans adapt to extreme underwater environments? Experimental Biology, Boston, USA
31. Ari, C., Poff, A., Landon, C., Goldhagen, C.R., Mavromates, N., Kesl, S., Ward N.P., Fiorelli T.N., Van Putten A.J., Sherwood J.W., Arnold P., D’Agostino, D.P. (2015) Metabolic therapies improve mitochondrial morphology and function, Experimental Biology, Boston, USA
32. Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, D’Agostino DP; Effect of Sustaining Dietary Ketosis on the Hippocampal and Serum Metabolome of Sprague-Dawley Rats. Federation of American Societies for Experimental Biology Journal, March 2015, Boston, MA
33. Poff AM, Kesl SL, Ari C, Ward NP, Fiorelli TN, Rogers CQ, Van Putten AJ, Sherwood JW, D’Agostino DP. (2015) Development and characterization of exogenous ketone supplements – novel methods of inducing therapeutic ketosis; Glut1 Deficiency Foundation Conference, Orlando, FL, USA
34. Ari C, Poff A.M., Kesl S.L, Goldhagen C.R., Murdun C, D’Agostino D.P. (2015) Chronic administration of exogenous ketone supplements reduces anxiety in Sprague-Dawley rats, Glut1 Deficiency Foundation Conference, Orlando, FL, USA
35. Ari C, Murdun C, Goldhagen C, Rogers C, D`Agostino D.P. (2015) Elevated blood ketone levels increase the latency of anaesthetic induction in GLUT1 mouse model, Glut1 Deficiency Foundation Conference, Orlando, FL, USA
36. Ari C, Murdun C, Goldhagen C, Rogers C, D`Agostino D.P. (2015) The effect of ketogenic diet and ketone supplementation on the motor function of `GLUT1 deficiency mouse model, Glut1 Deficiency Foundation Conference, Orlando, FL, USA
37. Ari, C., D`Agostino, D.P. (2015) Melanosome aggregations might cause giant manta ray skin change color, American Elasmobranch Society Meeting, Reno, USA
38. Ari C, Poff A.M., Kesl S.L, Goldhagen C.R., Murdun C, D’Agostino D.P. (2016) Chronic administration of exogenous ketone supplements reduces anxiety in Sprague-Dawley rats, 1st Annual Conference on Nutritional ketosis and Metabolic Therapeutics, Tampa, FL, USA
39. Ari C, Murdun C, Goldhagen C, Rogers C, D`Agostino D.P. (2016) Elevated blood ketone levels increase the latency of anaesthetic induction in GLUT1 mouse model, 1st Annual Conference on Nutritional ketosis and Metabolic Therapeutics, Tampa, FL, USA
40. Ari C, Murdun C, Goldhagen C, Rogers C, D`Agostino D.P. (2016) The effect of ketogenic diet and ketone supplementation on the motor function of `GLUT1 deficiency mouse model, 1st Annual Conference on Nutritional ketosis and Metabolic Therapeutics, Tampa, FL, USA
41. Ari, C, Decker, S., Ford, J., D`Agostino, D.P. (2016) What can we learn from deep-diving elasmobranchs to help humans adapt to extreme underwater environments? 1st Annual Conference on Nutritional ketosis and Metabolic Therapeutics, Tampa, FL, USA
42. Ari, C; Murdun, C; Goldhagen, C; Rogers, C; D`Agostino, D.P. (2016) Elevated blood ketone levels increase the latency of anesthetic induction in GLUT1 mouse model, International Behavioral Neuroscience Society Meeting, Budapest, Hungary
43. Ari, C; Kovacs, Z; Juhasz, G; Murdun, C; Goldhagen, CR.; Koutnik, A; Poff, A.M.; Kesl, S.L.; D’Agostino, D.P.(2016) Exogenous ketone supplements reduce anxiety-related behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk rats, International Behavioral Neuroscience Society Meeting, Budapest, Hungary
44. Ari, C; Kovacs, Z; Juhasz, G; Murdun, C; Goldhagen, CR.; Koutnik, A; Poff, A.M.; Kesl, S.L.; D’Agostino, D.P.(2016) Exogenous ketone supplements reduce anxiety-related behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk rats, Ketogenic Therapies Meeting, Banff, Canada
45. Ari, C; Koutnik, A.P; DeBlasi, J; Landon, C; Dean, J.B; D`Agostino, D.P. (2017) Comparison of Exogenous Ketone Supplements on Delayed Latency to CNS Oxygen Toxicity (CNSOT) Seizures, Metabolic Therapeutics Conference, Tampa
46. Ari, C; Koutnik, A.P; DeBlasi, J; Landon, C; Dean, J.B; D`Agostino, D.P. (2017) Comparison of Exogenous Ketone Supplements on Delayed Latency to CNS Oxygen Toxicity (CNSOT) Seizures, Office of Naval Research Annual Review Meeting, San Diego, USA
47. Arszovszki, A; D`Agostino, D.P; Kovacs, Z; Murdun, C; Goldhagen, C; Koutnik, A; Ari, C. (2017) Exogenous ketone supplementation improved motor function in rodent models Federation of European Neurosience Societies, Pecs, Hungary
48. Kovács, Z; D’Agostino, P.D; Dobolyi, A; Ari, C. (2017) Beneficial effect of ketone supplements on absence-like epileptic activity and anxiety-like behavior in Wag/Rij rats, Federation of European Neurosience Societies, Pecs, Hungary
49. Ari C, Kovács Z, Murdun C, Koutnik A.P., Goldhagen C.R., Rogers R, Park C, Bharwani S, Diamond D.M., D’Agostino D.P. (2018) Exogenous ketones lower blood glucose level, Experimental Biology Conference, San Diego, USA
50. Ari C, Koutnik A.P., DeBlasi J., Landon C., Vallas J., Bharwani S., Dean J.B., D`Agostino D.P. (2018) Comparison of Exogenous Ketone Supplements on Latency to CNS Oxygen Toxicity Seizures in Middle-Aged Rats, Experimental Biology Conference, San Diego, USA
51. Ari C., Zippert M., D`Agostino D.P. (2018) Neuroregeneration improved by ketones, Experimental Biology Conference, San Diego, USA
52. Csilla Ari, Cem Murdun, Andrew P. Koutnik, Craig R. Goldhagen, Christopher Rogers, Collin Park, Sahil Bharwani, David M. Diamond, Mark S. Kindy, Dominic P. D’Agostino, Zsolt Kovács (2019) Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models, Metabolic Health Summit, Los Angeles, USA
53. Csilla Ari, Cem Murdun, Craig Goldhagen, Andrew Koutnik, Sahil Bharwani, David Diamond, Mark Kindy, Dominic P. D`Agostino, Zsolt Kovacs (2019) Exogenous Ketones Improved Motor Function in Pre-Clinical Rodent Models, Metabolic Health Summit, Los Angeles, USA
54. Csilla Ari, Dominic P. D`Agostino (2019) Neuroregeneration Improved by Ketone Supplementation in Primary Neuronal Cultures, Metabolic Health Summit, Los Angeles, USA
55. Collin Park, John Vallas, Raquel Sanford, Moriah Bernhart, Sahil Bharwani, David M. Diamond, Mark S. Kindy, Dominic P. D’Agostino, Csilla Ari (2019) Changes on the Density and Localization of GLUT1 and MCT1 Transporters of Cancer Cells Induced by Ketones, Metabolic Health Summit, Los Angeles, USA
56. Csilla Ari, Dominic P. D`Agostino, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen M. Fiore (2020) Changes in Individual and Team Cognition in High Stress Extreme Underwater Saturation Environment Under Intense Workload, Metabolic Health Summit, Los Angeles, USA
57. Csilla Ari, Dominic P. D`Agostino, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen M. Fiore (2020) Changes in Motor Function in Response to Living in an Extreme Underwater Saturation Environment under High Stress and Increased Workload, Metabolic Health Summit, Los Angeles, USA
58. Csilla Ari, Collin Park, John Vallas, Raquel Sanford, Moriah Bernhart, Sahil Bharwani, David M. Diamond, Mark S. Kindy, Dominic P. D’Agostino (2020) Changes on the Density and Localization of GLUT1 and MCT1 Transporters of Cancer Cells Induced by Ketones, Metabolic Health Summit, Los Angeles, USA
59. Csilla Ari, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen Fiore, Dominic P. D`Agostino (2020) Changes in Sensory Functions in Response to Living in an Extreme Underwater Saturation Environment, Metabolic Health Summit, Los Angeles, USA
60. Csilla Ari, Dominic P. D`Agostino, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen M. Fiore (2020) Changes in Individual and Team Cognition in High Stress Extreme Underwater Saturation Environment Under Intense Workload, Experimental Biology, San Diego, USA
61. Csilla Ari, Dominic P. D`Agostino, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen M. Fiore (2020) Changes in Motor Function in Response to Living in an Extreme Underwater Saturation Environment under High Stress and Increased Workload, Experimental Biology, San Diego, USA
62. Csilla Ari, Sahil Bharwani, Anand Rehsi, Sara Moss, Sonja Schmer-Galunder, Stephen Fiore, Dominic P. D`Agostino (2020) Changes in Sensory Functions in Response to Living in an Extreme Underwater Saturation Environment, Experimental Biology, San Diego, USA
63. Ari, Csilla, Cem Murdun, Craig Goldhagen, Andrew P. Koutnik, Sahil R. Bharwani, David M. Diamond, Mark Kindy, Dominic P. D’Agostino, and Zsolt Kovacs. 2020. "Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models" Nutrients 12, no. 8: 2459. https://doi.org/10.3390/nu12082459
64. Kovács Zsolt, Brunner Brigitta, D’Agostino P. Dominic and Ari Csilla (2021) Age- and Sex-Dependent Modulation of Exogenous Ketone Supplement-Evoked Effects on Blood Glucose and Ketone Body Levels in Wistar Albino Glaxo Rijswijk Rats. Front. Neurosci. 14:618422. doi: 10.3389/fnins.2020.618422
65. Koutnik AP, Favre ME, Noboa K, Sanchez-Gonzalez MA, Moss SE, Goubran B, Ari Csilla, Poff AM, Rogers CQ, DeBlasi JM, Samy B, Moussa M, Serrador JM and D’Agostino DP (2021) Human Adaptations to Multiday Saturation on NASA NEEMO. Front. Physiol. 11:610000. doi: 10.3389/fphys.2020.610000
66. Brunner, Brigitta, Enikő Rauch, Csilla Ari, Dominic P. D’Agostino, and Zsolt Kovács. 2021. "Enhancement of Ketone Supplements-Evoked Effect on Absence Epileptic Activity by Co-Administration of Uridine in Wistar Albino Glaxo Rijswijk Rats" Nutrients 13, no. 1: 234. https://doi.org/10.3390/nu13010234
67. Ivancarmine Gambardella, Raimondo Ascione, Dominic P. D’Agostino, Csilla Ari, Berhane Worku, Robert F. Tranbaugh, Natalia Ivascu, Jonathan Villena-Vargas, Leonard N. Girardi. Neuroprotection of ketosis in acute injury of the mammalian central nervous system: A meta-analysis. J Neurochem. 2021; 158: 105– 118. https://doi.org/10.1111/jnc.15341
68. Csilla Ari, Collin Park, John Vallas, Raquel Sanford, Sahil Bharwani, Byeong Cha, Mark Kindy, Dominic D'Agostino (2021), Changes in Density and Localization of GLUT1 and MCT1 Transporters of Cancer Cells Induced by Ketones. The FASEB Journal, 35:. https://doi.org/10.1096/fasebj.2021.35.S1.03574
69. Kovács, Zsolt, Brigitta Brunner, and Csilla Ari. (2021). "Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases" Nutrients 13, no. 7: 2197. https://doi.org/10.3390/nu13072197
70. Medeiros Andrielli M, Ari Csilla, Monteiro-Filho ELA (2021) Environmental factors involved in breaching behavior of manta rays in estuarine waters. Mar Ecol Prog Ser 674:203-219. https://doi.org/10.3354/meps13815
71. Brunner, Brigitta, Csilla Ari, Dominic P. D’Agostino, and Zsolt Kovács. 2021. "Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats" Nutrients 13, no. 11: 4082. https://doi.org/10.3390/nu13114082
Presentations
1. Ari, C. (2013) Past, present and future of manta rays, Keynote talk at the Oceanography-2013 Conference, Manta Ray Symposium, Orlando, FL, USA
2. Ari, C. (2013) First evidence of long term and rapid coloration changes of giant Manta rays (genus Manta) with implications on reliability of photo identification techniques, Manta Ray Symposium, Orlando, FL, USA
3. Ari, C. (2013) Coloration changes of manta rays, Oceania Chondrichtyan Society Meeting, Brisbane, AU
4. Ari, C. (2013) Researching manta ray brains, TedXTampaBay
http://www.youtube.com/watch?v=SCfsweIsqdA
5. Ari, C. (2014) Rapid and long-term coloration changes of manta rays, American Elasmobranch Society Meeting, Chattanooga, USA
6. Ari, C. (2014) Manta ray research and conservation projects, DEMA show, Las Vegas, USA
7. Ari, C. (2015) Neuroprotective metabolic therapies by the ketogenic enhancement of the Szentgyorgyi-Krebs cycle: studies in animal models, 3rd International Congress of Deuterium Depletion, Budapest, Hungary
8. Ari, C., D`Agostino, D.P. (2015) Sensory and cognitive experiments on giant manta rays, American Elasmobranch Society Meeting, Reno, USA
9. Ari, C. (2017) Delaying Latency to Hyperbaric Oxygen Induced CNS Oxygen Toxicity Seizures by Combinations of Exogenous Ketone Supplements, International Hyperbaric Medical Society, New Orleans, USA
Media
http://www.nature.com/nature/journal/v512/n7512/full/512009a.html
http://www.83degreesmedia.com/features/researchers020513.aspx
http://wusfnews.wusf.usf.edu/post/usf-professor-joins-nasa-research-bottom-ocean#stream/0
https://stpetecatalyst.com/usf-researchers-may-be-first-married-couple-in-underwater-nasa-mission/
Hungarian
https://ripost.hu/cikk-ez-a-magyar-n-kesziti-fel-a-hold-misszio-rhajosait
https://www.feol.hu/egyperces/egy-magyar-no-kesziti-fel-a-hold-misszio-urhajosait-3051662/
https://www.teol.hu/egyperces/egy-magyar-no-kesziti-fel-a-hold-misszio-urhajosait-1655258/
https://hvg.hu/tudomany/20190521_nasa_magyar_tudos_ari_csilla_bolygokozi_utazas_pszichologia
https://www.origo.hu/tudomany/20100330-ari-csilla-ordograja-az-egyetlen-magyar-rajakutato.html
https://www.nlcafe.hu/eletmod/20190522/hold-urhajos-magyar-kutato-felkeszites-ari-csilla/
https://www.lokal.hu/2019-05-elkepeszto-siker-csilla-kesziti-fel-a-holdmisszio-urhajosait/
https://ripost.hu/cikk-oriasi-kihivas-var-a-nasa-magyar-szakert-jere-aki-uzent-a-ripostnak
Italian
https://www.astronautinews.it/2019/05/samantha-cristoforetti-comandera-la-missione-neemo-23/